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Description
SLAMF8 Recombinant Rabbit mAb (S-1956-78)Product Specification Host Rabbit Antigen SLAMF8 Synonyms SLAM family member 8; B lymphocyte activator macrophage expressed; BCM like membrane protein; CD353; BLAME Immunogen Synthetic Peptide Location Membrane Accession Q9P0V8 Clone Number S 1956 78 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Ms, Rt Positive Sample mouse lung, mouse thymus, mouse spleen, rat lung, rat thymus, rat spleen Purification Protein A Concentration 0.
Product Specification
| Host | Rabbit |
| Antigen | SLAMF8 |
| Synonyms | SLAM family member 8; B-lymphocyte activator macrophage expressed; BCM-like membrane protein; CD353; BLAME |
| Immunogen | Synthetic Peptide |
| Location | Membrane |
| Accession | Q9P0V8 |
| Clone Number | S-1956-78 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Ms, Rt |
| Positive Sample | mouse lung, mouse thymus, mouse spleen, rat lung, rat thymus, rat spleen |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Ms, Rt |
Background
SLAMF8, also known as B-lymphocyte activator macrophage expressed (BLAME) or CD353, is a single-pass type I membrane protein belonging to the SLAM (Signaling Lymphocyte Activation Molecule) family. It is characterized by the presence of Ig-like domains and is primarily expressed in immune-related tissues such as the lymph node, spleen, and thymus. SLAMF8 has been identified as a potential new immune checkpoint molecule, with its high expression associated with poor prognosis in colorectal cancer. This protein is involved in immune regulation and may play a role in various immune responses, including those related to inflammation and autoimmune diseases.
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