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Description
α-Synuclein Recombinant Rabbit mAb (S-441-86)Product Specification Host Rabbit Antigen Synuclein Synonyms Non A beta component of AD amyloid, Non A4 component of amyloid precursor (NACP), SNCA, NACP, PARK1, alpha Synuclein; Syn Immunogen Recombinant Protein Location Cytoplasm, Nucleus, Membrane Accession P37840 Clone Number S 441 86 Antibody Type Recombinant mAb Application WB, IHC P, IP, IF Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical
Product Specification
| Host | Rabbit |
| Antigen | α-Synuclein |
| Synonyms | Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor (NACP), SNCA, NACP, PARK1, alpha-Synuclein; α-Syn |
| Immunogen | Recombinant Protein |
| Location | Cytoplasm, Nucleus, Membrane |
| Accession | P37840 |
| Clone Number | S-441-86 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, IP, IF |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IP | 1:50 | |
| IHC | 1:2000 | |
| IF | 1:1000 |
Background
Alpha-synuclein is a neuronal protein that regulates synaptic vesicle trafficking and subsequent neurotransmitter release. It is abundant in the brain, while smaller amounts are found in the heart, muscle and other tissues. In the brain, alpha-synuclein is found mainly in the axon terminals of presynaptic neurons. Within these terminals, alpha-synuclein interacts with phospholipids and proteins. Presynaptic terminals release chemical messengers, called neurotransmitters, from compartments known as synaptic vesicles. The release of neurotransmitters relays signals between neurons and is critical for normal brain function.
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